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Analysis of the Assembly Profiles for Mitochondrial- and Nuclear-DNA-Encoded Subunits into Complex I

Complex I of the respiratory chain is composed of at least 45 subunits that assemble together at the mitochondrial inner membrane. Defects in human complex I result in energy generation disorders and are also implicated in Parkinson's disease and altered apoptotic signaling. The assembly of thi...

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Detalhes bibliográficos
Main Authors: Lazarou, Michael, McKenzie, Matthew, Ohtake, Akira, Thorburn, David R., Ryan, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900046/
https://ncbi.nlm.nih.gov/pubmed/17438127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00074-07
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