Mutational analysis of the adeno-associated virus Rep68 protein: identification of critical residues necessary for site-specific endonuclease activity.

The Rep68 and Rep78 proteins of adeno-associated virus type 2 (AAV) are multifunctional proteins which contain overlapping amino acid sequences. They are required for viral replication and preferential integration of the AAV genome into a region of human chromosome 19. During the terminal resolution...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Walker, S L, Wonderling, R S, Owens, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.2722-2730.1997
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