Integrin α11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells

Integrin α11 (ITGA11/α11) is localized to stromal fibroblasts and commonly overexpressed in non-small-cell lung carcinoma (NSCLC). We hypothesized that stromal α11 could be important for the tumorigenicity of NSCLC cells. SV40 immortalized mouse embryonic fibroblasts established from wild-type (WT)...

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Autors principals: Zhu, Chang-Qi, Popova, Svetlana N., Brown, Ewan R. S., Barsyte-Lovejoy, Dalia, Navab, Roya, Shih, Warren, Li, Ming, Lu, Ming, Jurisica, Igor, Penn, Linda Z., Gullberg, Donald, Tsao, Ming-Sound
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913903/
https://ncbi.nlm.nih.gov/pubmed/17600088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703040104
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