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Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic β-cells

CHOP-10 (GADD153/DDIT-3) is a bZIP protein involved in differentiation and apoptosis. Its expression is induced in response to stresses such as nutrient deprivation, perturbation of the endoplasmic reticulum, redox imbalance, and UV exposure. Here we show that CHOP expression is induced in cultured...

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Detalhes bibliográficos
Main Authors: Lawrence, Michael C., McGlynn, Kathleen, Naziruddin, Bashoo, Levy, Marlon F., Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913886/
https://ncbi.nlm.nih.gov/pubmed/17615236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704618104
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