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Cell division is essential for elimination of the yeast [PSI(+)] prion by guanidine hydrochloride
Guanidine hydrochloride (Gdn·HCl) blocks the propagation of yeast prions by inhibiting Hsp104, a molecular chaperone that is absolutely required for yeast prion propagation. We had previously proposed that ongoing cell division is required for Gdn·HCl-induced loss of the [PSI(+)] prion. Subsequently...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913874/ https://ncbi.nlm.nih.gov/pubmed/17606924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701392104 |
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