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Role of cdk2 in the sequential phosphorylation/activation of C/EBPβ during adipocyte differentiation
Upon induction of differentiation, growth-arrested (G(1) phase) 3T3-L1 preadipocytes express CCAAT/enhancer binding protein-β (C/EBPβ), initiating a transcriptional cascade. C/EBPβ immediately undergoes a priming phosphorylation (on Thr(188)) by MAPK/ERK. However, the acquisition of DNA binding and...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913868/ https://ncbi.nlm.nih.gov/pubmed/17601773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703771104 |
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