Analysis of HSD3B7 knockout mice reveals that a 3α-hydroxyl stereochemistry is required for bile acid function

Primary bile acids are synthesized from cholesterol in the liver and thereafter are secreted into the bile and small intestine. Gut flora modify primary bile acids to produce secondary bile acids leading to a chemically diverse bile acid pool that is circulated between the small intestine and liver....

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Detaylı Bibliyografya
Asıl Yazarlar: Shea, Heidi C., Head, Daphne D., Setchell, Kenneth D. R., Russell, David W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913850/
https://ncbi.nlm.nih.gov/pubmed/17601774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705089104
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