Interspecies DNA Microarray Analysis Identifies WblA as a Pleiotropic Down-Regulator of Antibiotic Biosynthesis in Streptomyces

Using Streptomyces coelicolor microarrays to discover regulators of gene expression in other Streptomyces species, we identified wblA, a whiB-like gene encoding a putative transcription factor, as a down-regulator of doxorubicin biosynthesis in Streptomyces peucetius. Further analysis revealed that...

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Bibliografiske detaljer
Main Authors: Kang, Seung-Hoon, Huang, Jianqiang, Lee, Han-Na, Hur, Yoon-Ah, Cohen, Stanley N., Kim, Eung-Soo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913423/
https://ncbi.nlm.nih.gov/pubmed/17416669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01789-06
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