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Spontaneous trpY Mutants and Mutational Analysis of the TrpY Archaeal Transcription Regulator
Over 90% of Methanothermobacter thermautotrophicus mutants isolated as spontaneously resistant to 5-methyl tryptophan had mutations in trpY. Most were single-base-pair substitutions that identified separate DNA- and tryptophan-binding regions in TrpY. In vivo and in vitro studies revealed that DNA b...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913389/ https://ncbi.nlm.nih.gov/pubmed/17400746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00164-07 |
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