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Spontaneous trpY Mutants and Mutational Analysis of the TrpY Archaeal Transcription Regulator

Over 90% of Methanothermobacter thermautotrophicus mutants isolated as spontaneously resistant to 5-methyl tryptophan had mutations in trpY. Most were single-base-pair substitutions that identified separate DNA- and tryptophan-binding regions in TrpY. In vivo and in vitro studies revealed that DNA b...

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Detalhes bibliográficos
Main Authors: Čuboňová, L'ubomíra, Sandman, Kathleen, Karr, Elizabeth A., Cochran, Andrew J., Reeve, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913389/
https://ncbi.nlm.nih.gov/pubmed/17400746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00164-07
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