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Mutations in rsmG, Encoding a 16S rRNA Methyltransferase, Result in Low-Level Streptomycin Resistance and Antibiotic Overproduction in Streptomyces coelicolor A3(2)

Certain str mutations that confer high- or low-level streptomycin resistance result in the overproduction of antibiotics by Streptomyces spp. The str mutations that confer the high-level resistance occur within rpsL, which encodes the ribosomal protein S12, while those that cause low-level resistanc...

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Detalhes bibliográficos
Main Authors: Nishimura, Kenji, Hosaka, Takeshi, Tokuyama, Shinji, Okamoto, Susumu, Ochi, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913335/
https://ncbi.nlm.nih.gov/pubmed/17384192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01776-06
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