Pharmacokinetics and Tolerability of a Higher Rifampin Dose versus the Standard Dose in Pulmonary Tuberculosis Patients

Rifampin is a key drug for tuberculosis (TB) treatment. The available data suggest that the currently applied 10-mg/kg of body weight dose of rifampin may be too low and that increasing the dose may shorten the treatment duration. A double-blind randomized phase II clinical trial was performed to in...

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Autores principales: Ruslami, Rovina, Nijland, Hanneke M. J., Alisjahbana, Bachti, Parwati, Ida, van Crevel, Reinout, Aarnoutse, Rob E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913243/
https://ncbi.nlm.nih.gov/pubmed/17452486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01550-06
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