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A Molecular Dynamics Study of Slow Base Flipping in DNA using Conformational Flooding

Individual DNA bases are known to be able to flip out of the helical stack, providing enzymes with access to the genetic information otherwise hidden inside the helix. Consequently, base flipping is a necessary first step to many more complex biological processes such as DNA transcription or replica...

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Autori principali: Bouvier, Benjamin, Grubmüller, Helmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913169/
https://ncbi.nlm.nih.gov/pubmed/17496048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.091751
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