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The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.

Completion of an early step in the human immunodeficiency virus type 1 (HIV-1) life cycle requires incorporation into virions of the cellular peptidyl-prolyl isomerase cyclophilin A (CyPA) by the Gag polyprotein. Elucidation of the biochemical role of CyPA would be aided by a detailed analysis of th...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Braaten, D, Ansari, H, Luban, J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1997
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.2107-2113.1997
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