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Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes.

An essential oncogenic determinant of subgroup D human adenovirus type 9 (Ad9), which uniquely elicits estrogen-dependent mammary tumors in rats, is encoded by early region 4 open reading frame 1 (E4 ORF1). Whereas Ad9 E4 ORF1 efficiently induces transformed foci on the established rat embryo fibrob...

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Publicat a:J Virol
Autors principals: Weiss, R S, Lee, S S, Prasad, B V, Javier, R T
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191256/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.1857-1870.1997
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