Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line.

We tested the ability of a recombinant adeno-associated virus (rAAV) vector to express and integrate exogenous DNA into human hematopoietic cells in the absence of selection. We developed an rAAV vector, AAV-tNGFR, carrying a truncated rat nerve growth factor receptor (tNGFR) cDNA as a cell surface...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Malik, P, McQuiston, S A, Yu, X J, Pepper, K A, Krall, W J, Podsakoff, G M, Kurtzman, G J, Kohn, D B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191246/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032306/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.1776-1783.1997
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