Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR.

Replication of the human immunodeficiency virus type 1 (HIV-1) is inhibited by interferons (IFNs), and the IFN-inducible protein kinase PKR is thought to mediate this effect by regulating protein synthesis. Here we report that ectopic expression of dominant negative PKR mutants in Jurkat cells induc...

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Pubblicato in:	J Virol
Autori principali:	Nagai, K, Wong, A H, Li, S, Tam, W N, Cuddihy, A R, Sonenberg, N, Mathews, M B, Hiscott, J, Wainberg, M A, Koromilas, A E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1718-1725.1997
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