Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR.

Replication of the human immunodeficiency virus type 1 (HIV-1) is inhibited by interferons (IFNs), and the IFN-inducible protein kinase PKR is thought to mediate this effect by regulating protein synthesis. Here we report that ectopic expression of dominant negative PKR mutants in Jurkat cells induc...

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Detalhes bibliográficos
Main Authors: Nagai, K, Wong, A H, Li, S, Tam, W N, Cuddihy, A R, Sonenberg, N, Mathews, M B, Hiscott, J, Wainberg, M A, Koromilas, A E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191238/
https://ncbi.nlm.nih.gov/pubmed/8995707
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