Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.

CXCR4 (also termed fusin, LESTR, or HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains. CXCR4 acts as a coreceptor for syncytium-inducing human immunodeficiency virus type 1 (HIV-1) strains, conferring entry into CD4+ cells. We show here that...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	McKnight, A, Wilkinson, D, Simmons, G, Talbot, S, Picard, L, Ahuja, M, Marsh, M, Hoxie, J A, Clapham, P R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1692-1696.1997
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