Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.

CXCR4 (also termed fusin, LESTR, or HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains. CXCR4 acts as a coreceptor for syncytium-inducing human immunodeficiency virus type 1 (HIV-1) strains, conferring entry into CD4+ cells. We show here that...

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Detalhes bibliográficos
Main Authors: McKnight, A, Wilkinson, D, Simmons, G, Talbot, S, Picard, L, Ahuja, M, Marsh, M, Hoxie, J A, Clapham, P R
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191233/
https://ncbi.nlm.nih.gov/pubmed/8995702
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