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Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1.

CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in which this region was exchanged for that of h...

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Udgivet i:J Virol
Principais autores: Simon, J H, Stumbles, P, Signoret, N, Somoza, C, Puklavec, M, Sattentau, Q J, Barclay, A N, James, W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191204/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1476-1484.1997
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