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Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors.

One hope to maintain the benefits of antiviral therapy against the human immunodeficiency virus type 1 (HIV-1), despite the development of resistance, is the possibility that resistant variants will show decreased viral fitness. To study this possibility, HIV-1 variants showing high-level resistance...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Croteau, G, Doyon, L, Thibeault, D, McKercher, G, Pilote, L, Lamarre, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1089-1096.1997
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