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Pharmacological manipulation of cyclo-oxygenase-2 in the inflamed hydronephrotic kidney.

1. Bradykinin (BK, 1 microgram) caused a small (2 fold at 6 h) increase in prostaglandin E2 (PGE2) in the normal rabbit kidney, perfused ex vivo. This was exaggerated (6 fold at 6 h) in the hydronephrotic kidney (HNK). The exaggerated release of PGE2 was attenuated by cycloheximide, an inhibitor of...

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Bibliografische gegevens
Hoofdauteurs: Seibert, K., Masferrer, J. L., Needleman, P., Salvemini, D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909763/
https://ncbi.nlm.nih.gov/pubmed/8882591
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