Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.

The enzyme cyclo-oxygenase catalyses the oxygenation of arachidonic acid, leading to the formation of prostaglandins. Recently two forms of cyclo-oxygenase have been described: a constitutive (COX-1) enzyme present in most cells and tissues, and an inducible (COX-2) isoenzyme observed in many cells...

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Main Authors: Gierse, J K, Hauser, S D, Creely, D P, Koboldt, C, Rangwala, S H, Isakson, P C, Seibert, K
格式: Artigo
語言:Inglês
出版: 1995
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136387/
https://ncbi.nlm.nih.gov/pubmed/7832763
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