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Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

Cyclo-oxygenase is expressed in cells in two distinct isoforms. Cyclo-oxygenase-1 is present constitutively whilst cyclo-oxygenase-2 is expressed primarily after inflammatory insult. The activity of cyclo-oxygenase-1 and -2 results in the production of a variety of potent biological mediators (the p...

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Bibliografski detalji
Glavni autori: Mitchell, Jane A, Warner, Timothy D
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571744/
https://ncbi.nlm.nih.gov/pubmed/10578123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702897
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