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Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy
Cyclo-oxygenase is expressed in cells in two distinct isoforms. Cyclo-oxygenase-1 is present constitutively whilst cyclo-oxygenase-2 is expressed primarily after inflammatory insult. The activity of cyclo-oxygenase-1 and -2 results in the production of a variety of potent biological mediators (the p...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571744/ https://ncbi.nlm.nih.gov/pubmed/10578123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702897 |
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