Selective and functional 5-hydroxytryptamine4 receptor antagonism by SB 207266.

1. The pharmacology of a novel 5-HT4 receptor antagonist, SB 207266 has been evaluated in vitro in the guinea-pig distal colon longitudinal muscle myenteric plexus (LMMP) and in vivo in the dog Heidenhain pouch. 2. SB 207266 is a highly potent antagonist of 5-HT-evoked, cholinergically-mediated cont...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wardle, K. A., Bingham, S., Ellis, E. S., Gaster, L. M., Rushant, B., Smith, M. I., Sanger, G. J.
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909720/
https://ncbi.nlm.nih.gov/pubmed/8762092
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