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Effects of a serotonin 5-HT(4) receptor antagonist SB-207266 on gastrointestinal motor and sensory function in humans

BACKGROUND—Serotonin 5-HT(4) receptors are located on enteric cholinergic neurones and may regulate peristalsis. 5-HT(4) receptors on primary afferent neurones have been postulated to modulate visceral sensation. While 5-HT(4) agonists are used as prokinetic agents, the physiological role of 5-HT(4)...

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Detalhes bibliográficos
Main Authors: Bharucha, A, Camilleri, M, Haydock, S, Ferber, I, Burton, D, Cooper, S, Tompson, D, Fitzpatrick, K, Higgins, R, Zinsmeister, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728108/
https://ncbi.nlm.nih.gov/pubmed/11034583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.5.667
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