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Potent antagonism by BIM-23056 at the human recombinant somatostatin sst5 receptor.

We have investigated the effects of somatostatin (SRIF) and the linear octapeptide BIM-23056 on changes in intracellular calcium ion concentration ([Ca2+]i) and on the formation of inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) in CHO-K1 cells transfected with the human recombinant SRIF sst5 receptor....

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Bibliographic Details
Main Authors: Wilkinson, G. F., Thurlow, R. J., Sellers, L. A., Coote, J. E., Feniuk, W., Humphrey, P. P.
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909702/
https://ncbi.nlm.nih.gov/pubmed/8762063
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