Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber.

1. The macrolide tacrolimus (FK506), used as an immunosuppressant, is a cytochrome P450 (CYP) 3A substrate in the liver. The metabolism of tacrolimus and the transport of its metabolites in the pig gut was studied in the Ussing chamber. Tacrolimus and its metabolites were quantified by h.p.l.c./mass...

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Detaylı Bibliyografya
Asıl Yazarlar: Lampen, A., Christians, U., Gonschior, A. K., Bader, A., Hackbarth, I., von Engelhardt, W., Sewing, K. F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909570/
https://ncbi.nlm.nih.gov/pubmed/8732283
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