Mutation of lysine residues in the nucleotide binding segments of the poliovirus RNA-dependent RNA polymerase.

The poliovirus 3D RNA-dependent RNA polymerase contains two peptide segments previously shown to cross-link to nucleotide substrates via lysine residues. To determine which lysine residue(s) might be implicated in catalytic function, we engineered mutations to generate proteins with leucine residues...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Richards, O C, Baker, S, Ehrenfeld, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190949/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8564-8570.1996
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