Mutation of lysine residues in the nucleotide binding segments of the poliovirus RNA-dependent RNA polymerase.
The poliovirus 3D RNA-dependent RNA polymerase contains two peptide segments previously shown to cross-link to nucleotide substrates via lysine residues. To determine which lysine residue(s) might be implicated in catalytic function, we engineered mutations to generate proteins with leucine residues...
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| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190949/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8564-8570.1996 |
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