Protective effect of NO on gastric lesions and inhibition of expression of gastric inducible NOS by flurbiprofen and its nitro-derivative, nitroflurbiprofen.

Nitroflurbiprofen (NFP) causes significantly less gastric lesions than flurbiprofen (FP), probably because of its capacity to release nitric oxide (NO) in the stomach. Lipopolysaccharide (LPS), which induces the expression of an inducible type of NO synthase (iNOS) in rat stomach, also reduces gastr...

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Detalhes bibliográficos
Main Authors: Mariotto, S., Menegazzi, M., Carcereri de Prati, A., Cuzzolin, L., Adami, A., Suzuki, H., Benoni, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909099/
https://ncbi.nlm.nih.gov/pubmed/8528547
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