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Antinociceptive activity of the tachykinin NK1 receptor antagonist, CP-99,994, in conscious gerbils.

1. The ability of CP-99,994, and its less active enantiomer, CP-100,263, to inhibit spontaneous behaviours and hyperalgesia induced by central infusion of the NK1 receptor agonist, GR73632 or intraplantar injection of formalin was investigated in rats and gerbils. 2. GR73632 (3 pmol, i.c.v.)-induced...

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Bibliografische gegevens
Hoofdauteurs: Rupniak, N. M., Webb, J. K., Williams, A. R., Carlson, E., Boyce, S., Hill, R. G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909089/
https://ncbi.nlm.nih.gov/pubmed/8528583
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