Central antitussive activity of the NK(1) and NK(2) tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat

1. The purpose of this study was to investigate the antitussive activity and sites of action of the NK(1) and NK(2) tachykinin receptor antagonists, CP-99,994, SR 48968, and the racemate of SR 48968, SR 48212A in the cat and guinea-pig. 2. Guinea-pigs were dosed subcutaneously (s.c.) with CP-99,994,...

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Detalhes bibliográficos
Main Authors: Bolser, Donald C, DeGennaro, Frances C, O'Reilly, Sandra, McLeod, Robbie L, Hey, John A
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564671/
https://ncbi.nlm.nih.gov/pubmed/9154323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701111
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