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Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm.

We introduced various mutations into the activation and RNA binding domains of human immunodeficiency virus type 1 (HIV-1) Tat in order to develop a novel and potent transdominant Tat protein and to characterize its mechanism of action. The different mutant Tat proteins were characterized for their...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Orsini, M J, Debouck, C M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892930/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8055-8063.1996
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