Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm.

We introduced various mutations into the activation and RNA binding domains of human immunodeficiency virus type 1 (HIV-1) Tat in order to develop a novel and potent transdominant Tat protein and to characterize its mechanism of action. The different mutant Tat proteins were characterized for their...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Orsini, M J, Debouck, C M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8055-8063.1996
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