Use of transdominant mutants of the origin-binding protein (UL9) of herpes simplex virus type 1 to define functional domains.

UL9, the origin-binding protein of herpes simplex virus type 1, contains six sequence motifs conserved in a large superfamily of RNA and DNA helicases. Single-amino-acid substitution mutations in these motifs inactivate UL9 function in vivo (R. Martinez, L. Shao, and S. K. Weller, J. Virol. 66:6735-...

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Pubblicato in:	J Virol
Autori principali:	Malik, A K, Weller, S K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7859-7866.1996
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