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Use of transdominant mutants of the origin-binding protein (UL9) of herpes simplex virus type 1 to define functional domains.

UL9, the origin-binding protein of herpes simplex virus type 1, contains six sequence motifs conserved in a large superfamily of RNA and DNA helicases. Single-amino-acid substitution mutations in these motifs inactivate UL9 function in vivo (R. Martinez, L. Shao, and S. K. Weller, J. Virol. 66:6735-...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Malik, A K, Weller, S K
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7859-7866.1996
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