A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo.
To investigate the role of nitric oxide during vaccinia virus (VV) infection of mice, a recombinant VV encoding the inducible nitric oxide synthase (iNOS) gene (VV-HA-iNOS) was constructed. Following infection of immunocompromised or immunocompetent mice, the virus was highly attenuated compared wit...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7678-7685.1996 |
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