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The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.

ICP27 is an essential herpes simplex virus type 1 nuclear regulatory protein that is required for efficient viral gene expression. Although the mechanism by which ICP27 regulates genes is unknown, a variety of evidence suggests that it functions posttranscriptionally, and recent studies indicate tha...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Mears, W E, Rice, S A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7445-7453.1996
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