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Transactivation of a Viral Target Gene by Herpes Simplex Virus ICP27 Is Posttranscriptional and Does Not Require the Endogenous Promoter or Polyadenylation Site

ICP27 is an essential herpes simplex virus type 1 (HSV-1) immediate-early protein that stimulates viral mRNA expression from many viral delayed-early and late genes during infection. One HSV-1 late gene which is highly dependent on ICP27 during infection is that encoding the glycoprotein C (gC). Her...

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Detalhes bibliográficos
Main Authors: Perkins, Keith D., Gregonis, Jennifer, Borge, Sarah, Rice, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224566/
https://ncbi.nlm.nih.gov/pubmed/12941897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9872-9884.2003
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