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Chronic treatment with the monoamine oxidase inhibitors clorgyline and pargyline down-regulates non-adrenoceptor [3H]-idazoxan binding sites in the rat brain.

1. The binding of [3H]-idazoxan in the presence of 10(-6) M (-)-adrenaline was used to quantitate non-adrenoceptor idazoxan binding sites (NAIBS) in the rat brain after treatment with various psychotropic drugs. 2. Chronic treatment (14 days) with the monoamine oxidase (MAO) inhibitors clorgyline (0...

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Main Authors: Olmos, G., Gabilondo, A. M., Miralles, A., Escriba, P. V., García-Sevilla, J. A.
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908014/
https://ncbi.nlm.nih.gov/pubmed/8385528
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