Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase.

1. This paper describes the pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase which is undergoing clinical evaluation. 2. ICI D2138 potently inhibited leukotriene synthesis in murine peritoneal macrophages (IC50 = 3 nM) and human blood (IC50 = 20 nM...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: McMillan, R. M., Spruce, K. E., Crawley, G. C., Walker, E. R., Foster, S. J.
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907929/
https://ncbi.nlm.nih.gov/pubmed/1334748
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker