N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure.

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin (NB-DNJ) is an inhibitor of human immunodeficiency virus (HIV) replication and HIV-induced syncytium formation in vitro. Although an NB-DNJ-mediated change in viral envelope N-glycan composition inhibits HIV entry at the level of post-CD4 bindi...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fischer, P B, Karlsson, G B, Dwek, R A, Platt, F M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.7153-7160.1996
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