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Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults

Preclinical evidence suggests that continuous low-dose daily (metronomic) chemotherapy may inhibit tumor endothelial cell proliferation (angiogenesis) and prevent tumor growth. This phase II study evaluated the feasibility of this antiangiogenic chemotherapy regimen in adults with recurrent malignan...

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Hlavní autoři: Kesari, Santosh, Schiff, David, Doherty, Lisa, Gigas, Debra C., Batchelor, Tracy T., Muzikansky, Alona, O’Neill, Alison, Drappatz, Jan, Chen-Plotkin, Alice S., Ramakrishna, Naren, Weiss, Stephanie E., Levy, Brenda, Bradshaw, Joanna, Kracher, Jean, Laforme, Andrea, Black, Peter McL., Folkman, Judah, Kieran, Mark, Wen, Patrick Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Duke University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907419/
https://ncbi.nlm.nih.gov/pubmed/17452651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-006
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