Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults

Preclinical evidence suggests that continuous low-dose daily (metronomic) chemotherapy may inhibit tumor endothelial cell proliferation (angiogenesis) and prevent tumor growth. This phase II study evaluated the feasibility of this antiangiogenic chemotherapy regimen in adults with recurrent malignan...

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Detalhes bibliográficos
Main Authors: Kesari, Santosh, Schiff, David, Doherty, Lisa, Gigas, Debra C., Batchelor, Tracy T., Muzikansky, Alona, O’Neill, Alison, Drappatz, Jan, Chen-Plotkin, Alice S., Ramakrishna, Naren, Weiss, Stephanie E., Levy, Brenda, Bradshaw, Joanna, Kracher, Jean, Laforme, Andrea, Black, Peter McL., Folkman, Judah, Kieran, Mark, Wen, Patrick Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2007
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907419/
https://ncbi.nlm.nih.gov/pubmed/17452651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-006
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