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Lentiviral Vpr usurps Cul4–DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

The replication of viruses depends on the cell cycle status of the infected cells. Viruses have evolved functions that alleviate restrictions imposed on their replication by the host. Vpr, an accessory factor of primate lentiviruses, arrests cells at the DNA damage checkpoint in G(2) phase of the ce...

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Autori principali: Hrecka, Kasia, Gierszewska, Magdalena, Srivastava, Smita, Kozaczkiewicz, Lukasz, Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Skowronski, Jacek
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906728/
https://ncbi.nlm.nih.gov/pubmed/17609381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702102104
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