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Laboratory evolution of one disulfide isomerase to resemble another

It is often difficult to determine which of the sequence and structural differences between divergent members of multigene families are functionally important. Here we use a laboratory evolution approach to determine functionally important structural differences between two distantly related disulfi...

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Autori principali: Hiniker, Annie, Ren, Guoping, Heras, Begoña, Zheng, Ying, Laurinec, Stephanie, Jobson, Richard W., Stuckey, Jeanne A., Martin, Jennifer L., Bardwell, James C. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906722/
https://ncbi.nlm.nih.gov/pubmed/17609373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704692104
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