Impaired up-regulation of CD70 and CD86 in naive (CD27(−)) B cells from patients with common variable immunodeficiency (CVID)

CVID is characterized by reduced serum levels of all switched immunoglobulin isotypes (IgG, IgA, IgE) predisposing patients to recurrent infections of their respiratory and gastrointestinal tract. Correspondingly, most CVID patients exhibit a severely decreased proportion of class switched memory B...

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Main Authors: GROTH, C, DRÄGER, R, WARNATZ, K, WOLFF-VORBECK, G, SCHMIDT, S, EIBEL, H, SCHLESIER, M, PETER, H-H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906432/
https://ncbi.nlm.nih.gov/pubmed/12100033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01883.x
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