Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles.

The Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys zinc fingers of retroviral nucleocapsid proteins are prime antiviral targets because of conservation of the Cys and His chelating residues and the absolute requirement of these fingers in both early and late phases of retroviral replication. We previously reported...

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Detalhes bibliográficos
Main Authors: Turpin, J A, Terpening, S J, Schaeffer, C A, Yu, G, Glover, C J, Felsted, R L, Sausville, E A, Rice, W G
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190642/
https://ncbi.nlm.nih.gov/pubmed/8709244
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